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A two-microRNA signature as a diagnostic and prognostic marker of pancreatic adenocarcinoma. Yu Y, Feng X, Cang S. 13 June 2018

Interferon λ cures persistent murine norovirus infection in the absence of adaptive immunity.

Disruption of the PRKCD–FBXO25–HAX-1 axis attenuates the apoptotic response and drives lymphomagenesis.

A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death.

Mutations in the voltage-gated potassium channel gene KCNH1 cause Temple-Baraitser syndrome and epilepsy.

Variation at HLA-DRB1 is associated with resistance to enteric fever.

Inactivating Mutations in NPC1L1 and Protection from Coronary Heart Disease.

Rescue of Hippo coactivator YAP1 triggers DNA damage–induced apoptosis in hematological cancers

Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine

Recurrent gain-of-function mutations of RHOA in diffuse-type gastric carcinoma

Recurrent PAX3-MAML3 fusion in biphenotypic sinonasal sarcoma

CTP synthase 1 deficiency in humans reveals its central role in lymphocyte proliferation

Activating Hotspot L205R Mutation in PRKACA and Adrenal Cushing's Syndrome

The ryanodine receptor store-sensing gate controls Ca2+ waves and Ca2+-triggered arrhythmias.

RIPK3 as a potential therapeutic target for Gaucher's disease.

Fas ligand–mediated immune surveillance by T cells is essential for the control of spontaneous B cell lymphomas.

Evolution and transmission of drug-resistant tuberculosis in a Russian population.

RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia.

Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes.