IMMUNOPEDIA is the most advanced and comprehensive relational database on the immunophenotypic evaluation of human neoplasms and normal tissues. It contains data from more than 4,500 quality references. Information about immunohistochemical markers and diseases can be accessed in more than one way making data mining exciting and informative. The data is compiled, reviewed, and entered by experts ensuring inclusion of only peer-reviewed quality citations.

Current version : IMMUNOPEDIA 5.0 (Released May 1, 2018).

Overexpression of SOX11 and TFE3 in Solid-Pseudopapillary Neoplasms of the Pancreas.

BCOR is a robust diagnostic immunohistochemical marker of genetically diverse high-grade endometrial stromal sarcoma, including tumors exhibiting variant morphology.

Data collection and representation is at the core of IMMUNOPEDIA. We would like to share certain conventions with our users.

• Markers' clones are listed when reported explicitly or deduced implicitly from manfacturer's catalogue if only one clone existed for that marker.
• If a clone is not reported and more than one clone exist for a given marker, a designation "CNS (Clone not specified)" is used.
• Markers are listed alphabetically in a single list "All markers" and also grouped alphabetically for shorter browsing menues. A search box is also provided.
• Diseases are listed alphabetically in a single list "All tissues/Organs" and also grouped according to specific organ/tissue for shorter browsing menues.
• A disease's name has the following format: "Disease, subtype, Tissue/Organ (optional)." Names are listed exactly as reported or according to WHO schemes.
• If a disease occurs in more than one organ and a tissue/organ is not specified in the cited reference then the disease is listed under "Site unspecified."
• The entities marked as [non-neo] includes data for non-neoplastic tissue/cells and may include data on reactive tissue/cells.
• Each fragment of data, whether on a marker or a disease, is linked to its reference source. The link to the reference(s) lists all the cited references.
• / = Alternative names of markers are separated by a forward slash "/" such as TM / CD141, Melan-A / MART1, and CD117 / c-Kit.
• ( ) = Qualifier to a marker's name is shown in parenthesis "( )" including (c) for cytoplasmic, (n) for nuclear, (p) for phosphorylated, and (h) for human.
• { } = Correlation of immunohistochemical expression with molecular data for certain markers is shown in curly brackets "{ }" such as p16 {HPV DNA+} indicates IHC expression of p16 in all HPV DNA positive cases and p16 {HPV DNA-} indicates IHC expression of p16 in all HPV DNA negative cases.
• [ ] = Quantitative IHC expression of Her2 validated against FISH data is shown in sqaure "[ ]" brackets. This represents overall incidence and not correlation. Thus, Her2 [IHC 2+/FISH+] represents incidence of all cases which are positive for Her2 amplification by FISH and also show 2+ Her2 expression by IHC. Likewise, Her2 [IHC 3+/FISH-] represents incidence of all cases which are negative for Her2 amplification by FISH but show 3+ Her2 expression by IHC.
•   This icon in the Build panel indicates the value of a marker as being "Good" in the differential diagnosis between adjacent diseases.
•   This icon in the Build panel indicates the value of a marker as being "Questionable" in the differential diagnosis between adjacent diseases.
•   This icon in the Build panel indicates the value of a marker as being "None" in the differential diagnosis between adjacent diseases.

Pathpedia encourages its users to suggest high-quality peer-reviewed articles to be included in the database. However, we do not guarantee inclusion of suggested articles if we deem those articles to be of lesser quality, dubious methods, published in languages other than English, and articles with little clinical significance.