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MicroRNA-21 Promotes Fibrosis of the Kidney by Silencing Metabolic Pathways

Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies

Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma

Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility

Mutations in SLC20A2 link familial idiopathic basal ganglia calcification with phosphate homeostasis

IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

IDH mutation impairs histone demethylation and results in a block to cell differentiation

Clonal selection drives genetic divergence of metastatic medulloblastoma

Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human

Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy

ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models

The Alarmin Interleukin-33 Drives Protective Antiviral CD8+ T Cell Responses

A CD74-dependent MHC class I endolysosomal cross-presentation pathway

Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export

Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke

Common variants at 11p13 are associated with susceptibility to tuberculosis

Common variants near MBNL1 and NKX2-5 are associated with infantile hypertrophic pyloric stenosis

Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility

Extrathymically generated regulatory T cells control mucosal TH2 inflammation

Expression of tumour-specific antigens underlies cancer immunoediting